LPAR5
| Receptor lizofosfatidne kiseline 5 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | LPAR5; GPR92 ; GPR93; KPG_010; LPA5 | ||||||||||
| Vanjski ID | OMIM: 606926 MGI: 2685918 HomoloGene: 10696 IUPHAR: GeneCards: LPAR5 Gene | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 57121 | 381810 | |||||||||
| Ensembl | ENSG00000184574 | ENSMUSG00000067714 | |||||||||
| UniProt | Q9H1C0 | n/a | |||||||||
| RefSeq (mRNA) | NM_020400 | XM_355812 | |||||||||
| RefSeq (protein) | NP_065133 | XP_355812 | |||||||||
| Lokacija (UCSC) |
Chr 12: 6.6 - 6.62 Mb |
Chr 6: 125.03 - 125.05 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
LPA5, receptor lizofosfatidne kiseline 5, je protein koji je kod čoveka kodiran LPAR5 gena.[1][2][3][4][5] LPA5 je G protein-spregnuti receptor koji vezuje lipidni signalni molekul lizofosfatidnu kiselinu (LPA).[6]
Vidi još
Literatura
- ^ Adhr, Consortium; Strom, Tim M.; White, Kenneth E.; Evans, Wayne E.; O'Riordan, Jeffery L.H.; Speer, Marcy C.; Lorenz-Depiereux, Bettina; Grabowski, Monika; Meitinger, Thomas (2000). „Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23”. Nat Genet. 26 (3): 345—8. PMID 11062477. doi:10.1038/81664.
- ^ Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (2001). „Discovery and mapping of ten novel G protein-coupled receptor genes”. Gene. 275 (1): 83—91. PMID 11574155. doi:10.1016/S0378-1119(01)00651-5.
- ^ Lee CW, Rivera R, Gardell S, Dubin AE, Chun J (2006). „GPR92 as a new G12/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5”. J Biol Chem. 281 (33): 23589—97. PMID 16774927. doi:10.1074/jbc.M603670200.
- ^ Kotarsky K, Boketoft A, Bristulf J, Nilsson NE, Norberg A, Hansson S, Owman C, Sillard R, Leeb-Lundberg LM, Olde B (2006). „Lysophosphatidic acid binds to and activates GPR92, a G protein-coupled receptor highly expressed in gastrointestinal lymphocytes”. J Pharmacol Exp Ther. 318 (2): 619—28. PMID 16651401. doi:10.1124/jpet.105.098848.
- ^ „Entrez Gene: GPR92 G protein-coupled receptor 92”.
- ^ Choi JW, Herr DR, Noguchi K, Yung YC, Lee CW, Mutoh T, Lin ME, Teo ST, Park KE, Mosley AN, Chun J (2010). „LPA Receptors: Subtypes and Biological Actions”. Annual Review of Pharmacology and Toxicology. 50 (1): 157—186. PMID 20055701. doi:10.1146/annurev.pharmtox.010909.105753.
Dodatna literatura
- Takeda S; Kadowaki S; Haga T; et al. (2002). „Identification of G protein-coupled receptor genes from the human genome sequence.”. FEBS Lett.. 520 (1-3): 97—101. PMID 12044878. doi:10.1016/S0014-5793(02)02775-8.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A.. 99 (26): 16899—903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899. - Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res.. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
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