GPR34
| G protein-spregnuti receptor 34 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | GPR34; | ||||||||||
| Vanjski ID | OMIM: 300241 MGI: 1346334 HomoloGene: 36174 IUPHAR: GPR34 GeneCards: GPR34 Gene | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 2857 | 23890 | |||||||||
| Ensembl | ENSG00000171659 | ENSMUSG00000040229 | |||||||||
| UniProt | Q9UPC5 | Q3USC5 | |||||||||
| RefSeq (mRNA) | NM_001033513 | NM_011823 | |||||||||
| RefSeq (protein) | NP_001028685 | NP_035953 | |||||||||
| Lokacija (UCSC) |
Chr X: 41.43 - 41.44 Mb |
Chr X: 12.79 - 12.8 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
GPR34, G protein-spregnuti receptor 34, je protein koji je kod čoveka kodiran GPR34 genom.[1][2][3]
G protein-spregnuti receptori, kao što je GPR34, su integralni membranski proteini koji sadrže 7 transmembranskih domaina (TM). Ti proteini prenose signale u unutrašnjost ćelije putem aktivacije heterotrimernih G proteina koji zatim aktiviraju razne efektorske proteine, što ultimatno dovodi do fiziološkog responsa.[3]
Literatura
- ^ Schoneberg T, Schulz A, Grosse R, Schade R, Henklein P, Schultz G, Gudermann T (1999). „A novel subgroup of class I G-protein-coupled receptors”. Biochim Biophys Acta. 1446 (1-2): 57—70. PMID 10395919.
- ^ Marchese A, Sawzdargo M, Nguyen T, Cheng R, Heng HH, Nowak T, Im DS, Lynch KR, George SR, O'dowd BF (1999). „Discovery of three novel orphan G-protein-coupled receptors”. Genomics. 56 (1): 12—21. PMID 10036181. doi:10.1006/geno.1998.5655.
- ^ а б „Entrez Gene: GPR34 G protein-coupled receptor 34”.
Dodatna literatura
- Hillier LD; Lennon G; Becker M; et al. (1997). „Generation and analysis of 280,000 human expressed sequence tags.”. Genome Res.. 6 (9): 807—28. PMID 8889549. doi:10.1101/gr.6.9.807.
- Jacobi FK; Broghammer M; Pesch K; et al. (2000). „Physical mapping and exclusion of GPR34 as the causative gene for congenital stationary night blindness type 1.”. Hum. Genet.. 107 (1): 89—91. PMID 10982042. doi:10.1007/s004390050017.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A.. 99 (26): 16899—903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899. - Ota T; Suzuki Y; Nishikawa T; et al. (2004). „Complete sequencing and characterization of 21,243 full-length human cDNAs.”. Nat. Genet.. 36 (1): 40—5. PMID 14702039. doi:10.1038/ng1285.
- Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res.. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
- Otsuki T; Ota T; Nishikawa T; et al. (2007). „Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.”. DNA Res.. 12 (2): 117—26. PMID 16303743. doi:10.1093/dnares/12.2.117.
- Engemaier E, Römpler H, Schöneberg T, Schulz A (2006). „Genomic and supragenomic structure of the nucleotide-like G-protein-coupled receptor GPR34.”. Genomics. 87 (2): 254—64. PMID 16338117. doi:10.1016/j.ygeno.2005.10.001.
- Oh JH; Yang JO; Hahn Y; et al. (2006). „Transcriptome analysis of human gastric cancer.”. Mamm. Genome. 16 (12): 942—54. PMID 16341674. doi:10.1007/s00335-005-0075-2.
Content Disclaimer
Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.
- The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
- There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
- It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
- Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
- Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.