GPR63
| G protein-spregnuti receptor 63 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | GPR63; PSP24(beta); PSP24B | ||||||||||
| Vanjski ID | OMIM: 606915 MGI: 2135884 HomoloGene: 12759 IUPHAR: GPR63 GeneCards: GPR63 Gene | ||||||||||
| |||||||||||
| Pregled RNK izražavanja | |||||||||||
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| podaci | |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 81491 | 81006 | |||||||||
| Ensembl | ENSG00000112218 | ENSMUSG00000040372 | |||||||||
| UniProt | Q9BZJ6 | Q8BZ93 | |||||||||
| RefSeq (mRNA) | NM_030784 | NM_030733 | |||||||||
| RefSeq (protein) | NP_110411 | NP_109658 | |||||||||
| Lokacija (UCSC) |
Chr 6: 97.35 - 97.39 Mb |
Chr 4: 25.06 - 25.1 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
GPR63, G protein-spregnuti receptor 63, je protein koji je kod čoveka kodiran GPR63 genom.[1]
G protein spregnuti receptori sadrže sedam transmembranskih domena i prenose ekstracelularne signale kroz heterotrimerne G proteine.[1]
Literatura
Dodatna literatura
- Kawasawa Y; Kume K; Nakade S; et al. (2000). „Brain-specific expression of novel G-protein-coupled receptors, with homologies to Xenopus PSP24 and human GPR45.”. Biochem. Biophys. Res. Commun.. 276 (3): 952—6. PMID 11027574. doi:10.1006/bbrc.2000.3569.
- Kawasawa Y, Kume K, Izumi T, Shimizu T (2000). „Mammalian PSP24s (alpha and beta isoforms) are not responsive to lysophosphatidic acid in mammalian expression systems.”. Biochem. Biophys. Res. Commun.. 276 (3): 957—64. PMID 11027575. doi:10.1006/bbrc.2000.3570.
- Lee DK; George SR; Cheng R; et al. (2001). „Identification of four novel human G protein-coupled receptors expressed in the brain.”. Brain Res. Mol. Brain Res.. 86 (1–2): 13—22. PMID 11165367. doi:10.1016/S0169-328X(00)00242-4.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A.. 99 (26): 16899—903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899. - Niedernberg A; Tunaru S; Blaukat A; et al. (2004). „Sphingosine 1-phosphate and dioleoylphosphatidic acid are low affinity agonists for the orphan receptor GPR63”. Cell. Signal.. 15 (4): 435—46. PMID 12618218. doi:10.1016/S0898-6568(02)00119-5.
- Mungall AJ; Palmer SA; Sims SK; et al. (2003). „The DNA sequence and analysis of human chromosome 6”. Nature. 425 (6960): 805—11. PMID 14574404. doi:10.1038/nature02055.
- Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res.. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
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