OR2A2
| Olfaktorni receptor, familija 2, potfamilija A, član 2 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | OR2A2; OR2A17P; OR2A2P; OR7-11; OST008 | ||||||||||
| Vanjski ID | MGI: 3030275 HomoloGene: 88438 GeneCards: OR2A2 Gene | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 442361 | 258648 | |||||||||
| Ensembl | ENSG00000221989 | ENSMUSG00000094200 | |||||||||
| UniProt | Q6IF42 | Q8VFS4 | |||||||||
| RefSeq (mRNA) | NM_001005480.2 | NM_146654.1 | |||||||||
| RefSeq (protein) | NP_001005480.2 | NP_666865.1 | |||||||||
| Lokacija (UCSC) |
Chr 7: 143.81 - 143.81 Mb |
Chr 6: 43.15 - 43.15 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Olfaktorni receptor 2A2 je protein koji je kod ljudi kodiran OR2A2 genom.[1]
Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[1]
Reference
Literatura
- Fuchs T; Malecova B; Linhart C; et al. (2003). „DEFOG: a practical scheme for deciphering families of genes”. Genomics. 80 (3): 295—302. PMID 12213199. doi:10.1006/geno.2002.6830.
- Hillier LW; Fulton RS; Fulton LA; et al. (2003). „The DNA sequence of human chromosome 7”. Nature. 424 (6945): 157—64. PMID 12853948. doi:10.1038/nature01782.
- Malnic B, Godfrey PA, Buck LB (2004). „The human olfactory receptor gene family”. Proc. Natl. Acad. Sci. U.S.A.. 101 (8): 2584—9. PMC 356993
. PMID 14983052. doi:10.1073/pnas.0307882100.
Vidi još
Spoljašnje veze
- OR2A2+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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