OR2C1
| Olfaktorni receptor, familija 2, potfamilija C, član 1 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | OR2C1; OLFmf3; OR2C2P | ||||||||||
| Vanjski ID | MGI: 106182 HomoloGene: 7459 GeneCards: OR2C1 Gene | ||||||||||
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| Pregled RNK izražavanja | |||||||||||
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| podaci | |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 4993 | 18312 | |||||||||
| Ensembl | ENSG00000168158 | ENSMUSG00000059043 | |||||||||
| UniProt | O95371 | P23275 | |||||||||
| RefSeq (mRNA) | NM_012368.2 | NM_008762.2 | |||||||||
| RefSeq (protein) | NP_036500.2 | NP_032788.2 | |||||||||
| Lokacija (UCSC) |
Chr 16: 3.41 - 3.41 Mb |
Chr 16: 3.84 - 3.84 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Olfaktorni receptor 2C1 je protein koji je kod ljudi kodiran OR2C1 genom.[1][2]
Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[2]
Reference
- ^ Centola M, Chen X, Sood R, Deng Z, Aksentijevich I, Blake T, Ricke DO, Chen X, Wood G, Zaks N, Richards N, Krizman D, Mansfield E, Apostolou S, Liu J, Shafran N, Vedula A, Hamon M, Cercek A, Kahan T, Gumucio D, Callen DF, Richards RI, Moyzis RK, Doggett NA, Collins FS, Liu PP, Fischel-Ghodsian N, Kastner DL (1999). „Construction of an ∼700-kb Transcript Map Around the Familial Mediterranean Fever Locus on Human Chromosome 16p13.3”. Genome Res. 8 (11): 1172—91. PMC 310791
. PMID 9847080. doi:10.1101/gr.8.11.1172.
- ^ а б „Entrez Gene: OR2C1 olfactory receptor, family 2, subfamily C, member 1”.
Literatura
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A.. 99 (26): 16899—903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
- Malnic B, Godfrey PA, Buck LB (2004). „The human olfactory receptor gene family”. Proc. Natl. Acad. Sci. U.S.A.. 101 (8): 2584—9. PMC 356993 . PMID 14983052. doi:10.1073/pnas.0307882100.
- Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)”. Genome Res.. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Vidi još
Spoljašnje veze
- OR2C1+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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