OR6C4
| Olfaktorni receptor, familija 6, potfamilija C, član 4 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | OR6C4; OR12-10 | ||||||||||
| Vanjski ID | MGI: 3030599 HomoloGene: 79371 GeneCards: OR6C4 Gene | ||||||||||
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| Pregled RNK izražavanja | |||||||||||
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| podaci | |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 341418 | 258315 | |||||||||
| Ensembl | ENSG00000179626 | ENSMUSG00000056853 | |||||||||
| UniProt | Q8NGE1 | n/a | |||||||||
| RefSeq (mRNA) | NM_001005494.1 | NM_146318 | |||||||||
| RefSeq (protein) | NP_001005494.1 | NP_666430 | |||||||||
| Lokacija (UCSC) |
Chr 12: 55.94 - 55.95 Mb |
Chr 10: 128.45 - 128.45 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Olfaktorni receptor 6C4 je protein koji je kod ljudi kodiran OR6C4 genom.[1]
Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[1]
Reference
Literatura
- Lauzurica P; Bragado R; López D; et al. (1992). „Asymmetric selection of T cell antigen receptor alpha- and beta-chains in HLA-B27 alloreactivity”. J. Immunol.. 148 (11): 3624—30. PMID 1316921.
- Youngblood K; Fruchter L; Ding G; et al. (1994). „Rheumatoid factors from the peripheral blood of two patients with rheumatoid arthritis are genetically heterogeneous and somatically mutated”. J. Clin. Invest.. 93 (2): 852—61. PMC 293948
. PMID 7509350. doi:10.1172/JCI117040. - Malnic B, Godfrey PA, Buck LB (2004). „The human olfactory receptor gene family”. Proc. Natl. Acad. Sci. U.S.A.. 101 (8): 2584—9. PMC 356993 . PMID 14983052. doi:10.1073/pnas.0307882100.
Vidi još
Spoljašnje veze
- OR6C4+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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