OR5M1
| Olfaktorni receptor, familija 5, potfamilija M, član 1 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | OR5M1; OR11-208; OST050 | ||||||||||
| Vanjski ID | MGI: 3030856 HomoloGene: 128087 GeneCards: OR5M1 Gene | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 390168 | 258580 | |||||||||
| Ensembl | ENSG00000255012 | ENSMUSG00000050128 | |||||||||
| UniProt | Q8NGP8 | A2ASU5 | |||||||||
| RefSeq (mRNA) | NM_001004740.1 | NM_146587.2 | |||||||||
| RefSeq (protein) | NP_001004740.1 | NP_666798.2 | |||||||||
| Lokacija (UCSC) |
Chr 11: 56.38 - 56.38 Mb |
Chr 2: 85.89 - 85.89 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Olfaktorni receptor 5M1 je protein koji je kod ljudi kodiran OR5M1 genom.[1]
Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[1]
Reference
Literatura
- Fuchs T; Malecova B; Linhart C; et al. (2003). „DEFOG: a practical scheme for deciphering families of genes.”. Genomics. 80 (3): 295—302. PMID 12213199. doi:10.1006/geno.2002.6830.
- Malnic B, Godfrey PA, Buck LB (2004). „The human olfactory receptor gene family.”. Proc. Natl. Acad. Sci. U.S.A.. 101 (8): 2584—9. PMC 356993
. PMID 14983052. doi:10.1073/pnas.0307882100.
Vidi još
Spoljašnje veze
- OR5M1+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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