OR5K1

Olfaktorni receptor, familija 5, potfamilija K, član 1
Identifikatori
Simboli OR5K1; HSHTPCRX10; HTPCRX10; OR3-8
Vanjski ID MGI3030007 HomoloGene45084 GeneCards: OR5K1 Gene
Pregled RNK izražavanja
podaci
Ortolozi
Vrsta Čovek Miš
Entrez 26339 259002
Ensembl ENSG00000232382 ENSMUSG00000049362
UniProt Q8NHB7 E9QAT7
RefSeq (mRNA) NM_001004736.2 NM_147000.2
RefSeq (protein) NP_001004736.2 NP_667211.2
Lokacija (UCSC) Chr 3:
98.19 - 98.19 Mb
Chr 16:
58.8 - 58.8 Mb
PubMed pretraga [1] [2]

Olfaktorni receptor 5K1 je protein koji je kod ljudi kodiran OR5K1 genom.[1][2]

Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[2]

Reference

  1. ^ Parmentier M; Libert F; Schurmans S; Schiffmann S; Lefort A; Eggerickx D; Ledent C; Mollereau C; Gerard C; Perret J; et al. (1992). „Expression of members of the putative olfactory receptor gene family in mammalian germ cells”. Nature. 355 (6359): 453—5. PMID 1370859. doi:10.1038/355453a0. 
  2. ^ а б „Entrez Gene: OR5K1 olfactory receptor, family 5, subfamily K, member 1”. 

Literatura

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