OR2T1
| Olfaktorni receptor, familija 2, potfamilija T, član 1 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | OR2T1; OR1-25 | ||||||||||
| Vanjski ID | MGI: 109304 HomoloGene: 74028 GeneCards: OR2T1 Gene | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 26696 | 18330 | |||||||||
| Ensembl | ENSG00000175143 | ENSMUSG00000072707 | |||||||||
| UniProt | O43869 | E9Q3K2 | |||||||||
| RefSeq (mRNA) | NM_030904.1 | NM_147027.2 | |||||||||
| RefSeq (protein) | NP_112166.1 | NP_667238.2 | |||||||||
| Lokacija (UCSC) |
Chr 1: 248.57 - 248.57 Mb |
Chr 14: 14.33 - 14.33 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Olfaktorni receptor 2T1 je protein koji je kod ljudi kodiran OR2T1 genom.[1][2]
Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[2]
Reference
- ^ Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (1998). „Distribution of olfactory receptor genes in the human genome”. Nat Genet. 18 (3): 243—50. PMID 9500546. doi:10.1038/ng0398-243.
- ^ а б „Entrez Gene: OR2T1 olfactory receptor, family 2, subfamily T, member 1”.
Literatura
- Fuchs T; Malecova B; Linhart C; et al. (2003). „DEFOG: a practical scheme for deciphering families of genes.”. Genomics. 80 (3): 295—302. PMID 12213199. doi:10.1006/geno.2002.6830.
- Malnic B, Godfrey PA, Buck LB (2004). „The human olfactory receptor gene family.”. Proc. Natl. Acad. Sci. U.S.A.. 101 (8): 2584—9. PMC 356993
. PMID 14983052. doi:10.1073/pnas.0307882100.
Vidi još
Spoljašnje veze
- OR2T1+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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