OR5F1
| Olfaktorni receptor, familija 5, potfamilija F, član 1 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | OR5F1; OR11-10 | ||||||||||
| Vanjski ID | OMIM: 608492 HomoloGene: 130524 GeneCards: OR5F1 Gene | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 338674 | n/a | |||||||||
| Ensembl | ENSG00000149133 | n/a | |||||||||
| UniProt | O95221 | n/a | |||||||||
| RefSeq (mRNA) | NM_003697.1 | n/a | |||||||||
| RefSeq (protein) | NP_003688.1 | n/a | |||||||||
| Lokacija (UCSC) |
Chr 11: 55.76 - 55.76 Mb | n/a | |||||||||
| PubMed pretraga | [1] | n/a | |||||||||
Olfaktorni receptor 5F1 je protein koji je kod ljudi kodiran OR5F1 genom.[1][2]
Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[2]
Reference
- ^ Buettner JA, Glusman G, Ben-Arie N, Ramos P, Lancet D, Evans GA (1998). „Organization and evolution of olfactory receptor genes on human chromosome 11”. Genomics. 53 (1): 56—68. PMID 9787077. doi:10.1006/geno.1998.5422.
- ^ а б „Entrez Gene: OR5F1 olfactory receptor, family 5, subfamily F, member 1”.
Literatura
- Fuchs T; Malecova B; Linhart C; et al. (2003). „DEFOG: a practical scheme for deciphering families of genes”. Genomics. 80 (3): 295—302. PMID 12213199. doi:10.1006/geno.2002.6830.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A.. 99 (26): 16899—903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899. - Malnic B, Godfrey PA, Buck LB (2004). „The human olfactory receptor gene family”. Proc. Natl. Acad. Sci. U.S.A.. 101 (8): 2584—9. PMC 356993 . PMID 14983052. doi:10.1073/pnas.0307882100.
Vidi još
Spoljašnje veze
- OR5F1+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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