OR2D3
| Olfaktorni receptor, familija 2, potfamilija D, član 3 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | OR2D3; OR11-89 | ||||||||||
| Vanjski ID | HomoloGene: 121514 GeneCards: OR2D3 Gene | ||||||||||
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| Pregled RNK izražavanja | |||||||||||
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| Vrsta | Čovek | Miš | |||||||||
| Entrez | 120775 | 194433 | |||||||||
| Ensembl | ENSG00000178358 | ENSMUSG00000069390 | |||||||||
| UniProt | Q8NGH3 | n/a | |||||||||
| RefSeq (mRNA) | NM_001004684.1 | NM_001005570.2 | |||||||||
| RefSeq (protein) | NP_001004684.1 | NP_001005570.2 | |||||||||
| Lokacija (UCSC) |
Chr 11: 6.94 - 6.94 Mb |
Chr 7: 106.89 - 106.89 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Olfaktorni receptor 2D3 je protein koji je kod ljudi kodiran OR2D3 genom.[1]
Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[1]
Vidi još
Reference
Literatura
- Fuchs T; Malecova B; Linhart C; et al. (2003). „DEFOG: a practical scheme for deciphering families of genes”. Genomics. 80 (3): 295—302. PMID 12213199. doi:10.1006/geno.2002.6830.
- Malnic B, Godfrey PA, Buck LB (2004). „The human olfactory receptor gene family”. Proc. Natl. Acad. Sci. U.S.A.. 101 (8): 2584—9. PMC 356993
. PMID 14983052. doi:10.1073/pnas.0307882100.
Spoljašnje veze
- OR2D3+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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