OR2S2
| Olfaktorni receptor, familija 2, potfamilija S, član 2 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | OR2S2; OR37A; OST715 | ||||||||||
| Vanjski ID | HomoloGene: 84331 GeneCards: OR2S2 Gene | ||||||||||
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| Pregled RNK izražavanja | |||||||||||
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| podaci | |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 56656 | 29845 | |||||||||
| Ensembl | ENSG00000122718 | ENSMUSG00000071000 | |||||||||
| UniProt | Q9NQN1 | Q8R469 | |||||||||
| RefSeq (mRNA) | NM_019897.2 | NM_019473.1 | |||||||||
| RefSeq (protein) | NP_063950.2 | NP_062346.1 | |||||||||
| Lokacija (UCSC) |
Chr 9: 35.96 - 35.96 Mb |
Chr 4: 43.85 - 43.86 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Olfaktorni receptor 2S2 je protein koji je kod ljudi kodiran OR2S2 genom.[1]
Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[1]
Reference
Literatura
- Strotmann J; Hoppe R; Conzelmann S; et al. (1999). „Small subfamily of olfactory receptor genes: structural features, expression pattern and genomic organization”. Gene. 236 (2): 281—91. PMID 10452948. doi:10.1016/S0378-1119(99)00275-9.
- Fuchs T; Malecova B; Linhart C; et al. (2003). „DEFOG: a practical scheme for deciphering families of genes”. Genomics. 80 (3): 295—302. PMID 12213199. doi:10.1006/geno.2002.6830.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A.. 99 (26): 16899—903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899. - Hoppe R, Breer H, Strotmann J (2004). „Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human”. Genomics. 82 (3): 355—64. PMID 12906860. doi:10.1016/S0888-7543(03)00116-2.
- Malnic B, Godfrey PA, Buck LB (2004). „The human olfactory receptor gene family”. Proc. Natl. Acad. Sci. U.S.A.. 101 (8): 2584—9. PMC 356993 . PMID 14983052. doi:10.1073/pnas.0307882100.
- Humphray SJ; Oliver K; Hunt AR; et al. (2004). „DNA sequence and analysis of human chromosome 9”. Nature. 429 (6990): 369—74. PMC 2734081 . PMID 15164053. doi:10.1038/nature02465.
- Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res.. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Vidi još
Spoljašnje veze
- OR2S2+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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