OR4D6
| Olfaktorni receptor, familija 4, potfamilija D, član 6 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | OR4D6; OR11-250 | ||||||||||
| Vanjski ID | MGI: 3031262 HomoloGene: 17339 GeneCards: OR4D6 Gene | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 219983 | 258673 | |||||||||
| Ensembl | ENSG00000166884 | ENSMUSG00000067524 | |||||||||
| UniProt | Q8NGJ1 | Q0VDY1 | |||||||||
| RefSeq (mRNA) | NM_001004708.1 | NM_146678.2 | |||||||||
| RefSeq (protein) | NP_001004708.1 | NP_666889.2 | |||||||||
| Lokacija (UCSC) |
Chr 11: 59.22 - 59.23 Mb |
Chr 19: 12.11 - 12.11 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Olfaktorni receptor 4D6 je protein koji je kod ljudi kodiran OR4D6 genom.[1]
Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[1]
Reference
Literatura
- Fuchs T; Malecova B; Linhart C; et al. (2003). „DEFOG: a practical scheme for deciphering families of genes.”. Genomics. 80 (3): 295—302. PMID 12213199. doi:10.1006/geno.2002.6830.
- Malnic B, Godfrey PA, Buck LB (2004). „The human olfactory receptor gene family.”. Proc. Natl. Acad. Sci. U.S.A.. 101 (8): 2584—9. PMC 356993
. PMID 14983052. doi:10.1073/pnas.0307882100.
Vidi još
Spoljašnje veze
- OR4D6+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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