OR2M2

Olfaktorni receptor, familija 2, potfamilija M, član 2
Identifikatori
Simboli OR2M2; OR2M2Q; OST423
Vanjski ID MGI: 3029998 HomoloGene: 121587 GeneCards: OR2M2 Gene
Ortolozi
Vrsta Čovek Miš
Entrez 391194 258443
Ensembl ENSG00000198601 ENSMUSG00000050742
UniProt Q96R28 n/a
RefSeq (mRNA) NM_001004688.1 NM_146451
RefSeq (protein) NP_001004688.1 NP_666662
Lokacija (UCSC) Chr 1:
248.34 - 248.34 Mb		 Chr 16:
19.2 - 19.2 Mb
PubMed pretraga [1] [2]

Olfaktorni receptor 2M2 je protein koji je kod ljudi kodiran OR2M2 genom.[1][2]

Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[2]

Reference

  1. ^ Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R (2002). „DEFOG: a practical scheme for deciphering families of genes”. Genomics. 80 (3): 295—302. PMID 12213199. doi:10.1006/geno.2002.6830. 
  2. ^ а б „Entrez Gene: OR2M2 olfactory receptor, family 2, subfamily M, member 2”. 

Literatura

  • Gregory SG; Barlow KF; McLay KE; et al. (2006). „The DNA sequence and biological annotation of human chromosome 1.”. Nature. 441 (7091): 315—21. PMID 16710414. doi:10.1038/nature04727. 

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