OR5AC2
| Olfaktorni receptor, familija 5, potfamilija AC, član 2 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | OR5AC2; HSA1 | ||||||||||
| Vanjski ID | MGI: 3030032 HomoloGene: 51800 GeneCards: OR5AC2 Gene | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 81050 | 258036 | |||||||||
| Ensembl | ENSG00000196578 | ENSMUSG00000052537 | |||||||||
| UniProt | Q9NZP5 | Q7TS40 | |||||||||
| RefSeq (mRNA) | NM_054106.1 | NM_001011808.1 | |||||||||
| RefSeq (protein) | NP_473447.1 | NP_001011808.1 | |||||||||
| Lokacija (UCSC) |
Chr 3: 97.81 - 97.81 Mb |
Chr 16: 59.2 - 59.2 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Olfaktorni receptor 5AC2 je protein koji je kod ljudi kodiran OR5AC2 genom.[1]
Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[1]
Reference
Literatura
- Rouquier S, Blancher A, Giorgi D (2000). „The olfactory receptor gene repertoire in primates and mouse: Evidence for reduction of the functional fraction in primates”. Proc. Natl. Acad. Sci. U.S.A.. 97 (6): 2870—4. PMC 16022
. PMID 10706615. doi:10.1073/pnas.040580197. - Muzny DM; Scherer SE; Kaul R; et al. (2006). „The DNA sequence, annotation and analysis of human chromosome 3”. Nature. 440 (7088): 1194—8. PMID 16641997. doi:10.1038/nature04728.
Vidi još
Spoljašnje veze
- OR5AC2+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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