OR2D2
| Olfaktorni receptor, familija 2, potfamilija D, član 2 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | OR2D2; OR11-610; OR2D1; hg27 | ||||||||||
| Vanjski ID | OMIM: 608494 MGI: 3030549 HomoloGene: 81541 GeneCards: OR2D2 Gene | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 120776 | 258776 | |||||||||
| Ensembl | ENSG00000166368 | ENSMUSG00000060503 | |||||||||
| UniProt | Q9H210 | Q8VG49 | |||||||||
| RefSeq (mRNA) | NM_003700.1 | NM_146780.2 | |||||||||
| RefSeq (protein) | NP_003691.1 | NP_666991.1 | |||||||||
| Lokacija (UCSC) |
Chr 11: 6.91 - 6.91 Mb |
Chr 7: 107.13 - 107.13 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Olfaktorni receptor 2D2 je protein koji je kod ljudi kodiran OR2D2 genom.[1][2]
Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[2]
Vidi još
Reference
- ^ Buettner JA, Glusman G, Ben-Arie N, Ramos P, Lancet D, Evans GA (1998). „Organization and evolution of olfactory receptor genes on human chromosome 11”. Genomics. 53 (1): 56—68. PMID 9787077. doi:10.1006/geno.1998.5422.
- ^ а б „Entrez Gene: OR2D2 olfactory receptor, family 2, subfamily D, member 2”.
Literatura
- Fuchs T; Malecova B; Linhart C; et al. (2003). „DEFOG: a practical scheme for deciphering families of genes”. Genomics. 80 (3): 295—302. PMID 12213199. doi:10.1006/geno.2002.6830.
- Malnic B, Godfrey PA, Buck LB (2004). „The human olfactory receptor gene family”. Proc. Natl. Acad. Sci. U.S.A.. 101 (8): 2584—9. PMC 356993
. PMID 14983052. doi:10.1073/pnas.0307882100.
Spoljašnje veze
- OR2D2+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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