OR2K2
| Olfaktorni receptor, familija 2, potfamilija K, član 2 | |||||||||||
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| Identifikatori | |||||||||||
| Simboli | OR2K2; HSHTPCRH06; HTPCRH06; OR2AN1P; OR2AR1P | ||||||||||
| Vanjski ID | MGI: 3030101 HomoloGene: 17436 GeneCards: OR2K2 Gene | ||||||||||
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| Pregled RNK izražavanja | |||||||||||
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| podaci | |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 26248 | 258922 | |||||||||
| Ensembl | ENSG00000171133 | ENSMUSG00000043385 | |||||||||
| UniProt | Q8NGT1 | A2AM35 | |||||||||
| RefSeq (mRNA) | NM_205859.1 | NM_146920.2 | |||||||||
| RefSeq (protein) | NP_995581.1 | NP_667131.2 | |||||||||
| Lokacija (UCSC) |
Chr 9: 114.09 - 114.09 Mb |
Chr 4: 58.78 - 58.79 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Olfaktorni receptor 2K2 je protein koji je kod ljudi kodiran OR2K2 genom.[1][2][3]
Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[3]
Reference
- ^ Parmentier M; Libert F; Schurmans S; Schiffmann S; Lefort A; Eggerickx D; Ledent C; Mollereau C; Gerard C; Perret J; et al. (1992). „Expression of members of the putative olfactory receptor gene family in mammalian germ cells”. Nature. 355 (6359): 453—5. PMID 1370859. doi:10.1038/355453a0.
- ^ Aloni R, Olender T, Lancet D (2007). „Ancient genomic architecture for mammalian olfactory receptor clusters”. Genome Biol. 7 (10): R88. PMC 1794568
. PMID 17010214. doi:10.1186/gb-2006-7-10-r88.
- ^ а б „Entrez Gene: OR2K2 olfactory receptor, family 2, subfamily K, member 2”.
Literatura
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A.. 99 (26): 16899—903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
- Malnic B, Godfrey PA, Buck LB (2004). „The human olfactory receptor gene family.”. Proc. Natl. Acad. Sci. U.S.A.. 101 (8): 2584—9. PMC 356993 . PMID 14983052. doi:10.1073/pnas.0307882100.
- Humphray SJ; Oliver K; Hunt AR; et al. (2004). „DNA sequence and analysis of human chromosome 9.”. Nature. 429 (6990): 369—74. PMC 2734081 . PMID 15164053. doi:10.1038/nature02465.
- Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res.. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Vidi još
Spoljašnje veze
- OR2K2+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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