OR5P2
| Olfaktorni receptor, familija 5, potfamilija P, član 2 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | OR5P2; JCG3; JCG4 | ||||||||||
| Vanjski ID | MGI: 3030336 HomoloGene: 72021 GeneCards: OR5P2 Gene | ||||||||||
| |||||||||||
| Pregled RNK izražavanja | |||||||||||
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| podaci | |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 120065 | 258734 | |||||||||
| Ensembl | ENSG00000183303 | ENSMUSG00000058014 | |||||||||
| UniProt | Q8WZ92 | Q8VG09 | |||||||||
| RefSeq (mRNA) | NM_153444.1 | NM_146739.1 | |||||||||
| RefSeq (protein) | NP_703145.1 | NP_666950.1 | |||||||||
| Lokacija (UCSC) |
Chr 11: 7.82 - 7.82 Mb |
Chr 7: 108.52 - 108.52 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Olfaktorni receptor 5P2 je protein koji je kod ljudi kodiran OR5P2 genom.[1]
Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[1]
Reference
Literatura
- Gaudin JC, Breuils L, Haertlé T (2002). „New GPCRs from a human lingual cDNA library”. Chem. Senses. 26 (9): 1157—66. PMID 11705801. doi:10.1093/chemse/26.9.1157.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A.. 99 (26): 16899—903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899. - Malnic B, Godfrey PA, Buck LB (2004). „The human olfactory receptor gene family”. Proc. Natl. Acad. Sci. U.S.A.. 101 (8): 2584—9. PMC 356993 . PMID 14983052. doi:10.1073/pnas.0307882100.
- Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res.. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Vidi još
Spoljašnje veze
- OR5P2+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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