OR5B12
| Olfaktorni receptor, familija 5, potfamilija B, član 12 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | OR5B12; OR11-241; OR5B12P; OR5B16; OST743 | ||||||||||
| Vanjski ID | MGI: 3031282 HomoloGene: 64904 GeneCards: OR5B12 Gene | ||||||||||
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| Pregled RNK izražavanja | |||||||||||
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| podaci | |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 390191 | 258696 | |||||||||
| Ensembl | ENSG00000172362 | ENSMUSG00000048456 | |||||||||
| UniProt | Q96R08 | Q8VFW9 | |||||||||
| RefSeq (mRNA) | NM_001004733.2 | NM_146701.1 | |||||||||
| RefSeq (protein) | NP_001004733.1 | NP_666912.1 | |||||||||
| Lokacija (UCSC) |
Chr 11: 58.21 - 58.21 Mb |
Chr 19: 12.92 - 12.92 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Olfaktorni receptor 5B12 je protein koji je kod ljudi kodiran OR5B12 genom.[1][2]
Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[2]
Reference
- ^ Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R (2002). „DEFOG: a practical scheme for deciphering families of genes”. Genomics. 80 (3): 295—302. PMID 12213199. doi:10.1006/geno.2002.6830.
- ^ а б „Entrez Gene: OR5B12 olfactory receptor, family 5, subfamily B, member 12”.
Literatura
- Malnic B, Godfrey PA, Buck LB (2004). „The human olfactory receptor gene family.”. Proc. Natl. Acad. Sci. U.S.A.. 101 (8): 2584—9. PMC 356993
. PMID 14983052. doi:10.1073/pnas.0307882100.
Vidi još
Spoljašnje veze
- OR5B12+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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