OR4D1
| Olfaktorni receptor, familija 4, potfamilija D, član 1 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | OR4D1; OR17-23; OR4D3; OR4D4P; TPCR16 | ||||||||||
| Vanjski ID | MGI: 3030298 HomoloGene: 44975 GeneCards: OR4D1 Gene | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 26689 | 258407 | |||||||||
| Ensembl | ENSG00000141194 | ENSMUSG00000060787 | |||||||||
| UniProt | Q15615 | Q5SW48 | |||||||||
| RefSeq (mRNA) | NM_012374.1 | NM_146412.2 | |||||||||
| RefSeq (protein) | NP_036506.1 | NP_666524.2 | |||||||||
| Lokacija (UCSC) |
Chr 17: 56.23 - 56.23 Mb |
Chr 11: 87.91 - 87.92 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Olfaktorni receptor 4D1 je protein koji je kod ljudi kodiran OR4D1 genom.[1][2]
Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[2]
Reference
- ^ Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). „Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species”. Genomics. 39 (3): 239—46. PMID 9119360. doi:10.1006/geno.1996.4490.
- ^ а б „Entrez Gene: OR4D1 olfactory receptor, family 4, subfamily D, member 1”.
Literatura
- Fuchs T; Malecova B; Linhart C; et al. (2003). „DEFOG: a practical scheme for deciphering families of genes.”. Genomics. 80 (3): 295—302. PMID 12213199. doi:10.1006/geno.2002.6830.
- Malnic B, Godfrey PA, Buck LB (2004). „The human olfactory receptor gene family.”. Proc. Natl. Acad. Sci. U.S.A.. 101 (8): 2584—9. PMC 356993
. PMID 14983052. doi:10.1073/pnas.0307882100.
Vidi još
Spoljašnje veze
- OR4D1+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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