OR4F5

OR4F5
Identifikatori
AlijasiOR4F5
Spoljašnji IDMGI: 3031123 HomoloGene: 128250 GeneCards: OR4F5
Ortolozi
VrsteČovekMiš
Entrez

79501

258399

Ensembl

ENSG00000186092

ENSMUSG00000061195

UniProt

Q8NH21

Q8VF49

RefSeq (mRNA)

NM_001005484

NM_146404

RefSeq (protein)

NP_001005484

NP_666516

Location (UCSC)n/aChr 2: 111.31 – 111.31 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Olfaktorni receptor familija 4 podfamilija F član 5 je protein koji je kod ljudi kodiran genom OR4F5.[4]

Funkcija

Olfaktorni receptori formiraju interakcije s molekulama mirisa u nosu, kako bi pokrenuli neuronski odgovor koji pokreće percepciju mirisa. Olfaktorni receptorski proteini članovi su velike porodice G-protein-spregnutih receptora (GPCR) koji proizlaze iz pojedinačnih gena za kodiranje eksona. Olfaktorni receptori dele strukturu 7-transmembranskog domena s mnogim neurotransmiterskim i hormonskim receptorima i odgovorni su za prepoznavanje i transdukciju mirisnih signala posredovanu G proteinom. Familija gena olfaktornih receptora najveća je u genomu. Nomenklatura dodeljena genima i proteinima olfaktornih receptora za ovaj organizam je nezavisna od drugih organizmima.

Trivija

OR4F5 prvi gen koji kodira protein na ljudskom hromozomu 1.

Reference

  1. ^ а б в GRCm38: Ensembl release 89: ENSMUSG00000061195 - Ensembl, May 2017
  2. ^ „Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  3. ^ „Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ „Entrez Gene: Olfactory receptor family 4 subfamily F member 5”. 

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